Gender Differences in Axial Spondyloarthritis: Women Are Not So Lucky

Axial Spondyloarthritis Flares - Whatever They Are.

Anti-IL17A in Axial Spondyloarthritis—Where Are We At?

Knowledge regarding the mechanisms of the IL17-IL23 pathway and its role in spondyloarthritis (SpA) has been pivotal to the development of IL-17 blockade in patients with axial SpA. Previously, only anti-TNF has proven to be clinically efficacious in patients with active disease, despite non-steroidal anti-inflammatory drugs and physiotherapy. However, up to 50% fail to achieve a clinically sig...

Non-radiographic axial spondyloarthritis and ankylosing spondylitis: what are the similarities and differences?

The development of the axial spondyloarthritis and ankylosing spondylitis (ASAS) classification criteria has had several implications for our understanding of the entire spectrum of spondyloarthritides (SpA). Going beyond the modified New York criteria, which concentrate on conventional radiographs of the sacroiliac joints (SIJ) for the classification of ankylosing spondylitis, the ASAS criteri...

Epidemiology of axial spondyloarthritis

Cytokine profiles in axial spondyloarthritis

OBJECTIVES Current studies concentrate on the cytokine network and its role in the pathogenesis of spondyloarthritis (SpA). In this study, we analyzed whether the serum cytokine profile (interleukins: IL-10, IL-11, IL-12, IL-15, IL-17, IL-23 and IL-33) correlates with demographic data, clinical manifestations, disease activity and treatment outcome in a group of patients with axial spondyloarth...